Monday, April 24th, 2017 - Momo Wisath Sae-Lee talks about using nematodes to study Alzheimer’s!

7Aug

While you are proabably familiar with Alzheimer's disease (AD), the microscopic creatures named nematodes/roundworms may be a bit more foreign. Believe it or not, these tiny worms have much more in common with humans than it seems, having already helped us unravel important cellular processes like programmed cell death and RNA interference that occur in humans as well as these worms. Futhermore, they may yet hold the key to unlocking a cure for AD! Listen in to hear Momo Wisath Sae-Lee tell us about how nematodes are helping to answer important questions like what makes certain types of neurons more vulnerable to degredation than others, what genetic risk factors can lead to neural degeneration, and how nematodes can help us screen future drugs to eradticate this debilitating disease.

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Monday, April 3rd, 2017 - Azat Akhmetov talks about using DNA to store information!

7Aug

This week, Azat Akhmetov tells us how silicon-based data storage may become a thing of the past thanks to a familiar but unlikely new way to store data: in DNA! While current storage methods are limited by natural resources, stability, and physical constraints, DNA serves as a way to surpass these limits and revolutionize the way data is stored and accessed. His research focuses on tackling the challenges left standing to make this intersting idea a reality; tune in to find out more!

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Monday, May 8th, 2017 - Stephen Jones talks about cellular aging!

7Aug

What is aging? How old you are, or maybe instead how well you maintain your health? Where does aging occur? In our organs, tissues, or even individual cells? These answers to these seemingly simple questions, are anything but. In this episode, Stephen Jones tells us how his study of individual cells using a "microfluidic" machine allows him to capture about a thousand individual cells at a time and watch them over their entire lives through each (division) replication, conflict, and catastrophe, thereby directly observing the cellular aging process. Using this work has allowed him to also shed light on the processes of cellular quiescence (taking a "break" from division) and silencing (how cells keep some parts of their DNA shut off), so we can understand how these vital cellular functions contribute to the aging process!

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Monday, May 29th, 2017 - Riddhiman Kannan uses humanized yeast to study evolution and disease!

7Aug

Did you know that allthough Saccharomyces cerevisiae (Baker’s yeast) and Homo sapiens (humans, us) are separated by a billion years in evolutionary time, nearly half (~47%) of the essential yeast genes can be substituted for by their corresponding human counterparts and the yeast are just fine?! On this episode, Riddhiman Kannan talks to us about how putting human genes into yeast can be used as a tool to more easily study human evolution and disease, and even help discover new therapies!

*NOTE* The recording of the interview comes in a few minutes after we actually started; sorry for the missing time!

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